Regulatory T Cells in Asthma and Airway Hyperresponsiveness
نویسندگان
چکیده
Regulatory T cells, or Tregs, have been shown to play a major role in reducing Th2 cell proliferation, potentially reducing (often significantly) airway-associated inflammation seen in airway diseases, such as asthma. These cells are characterized as a sub-population of T cells that maintain peripheral tolerance through a variety of biological mechanisms. Although Tregs make up only 5-10% of peripheral CD4 +
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